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Excretion, homeostasis and coordination

Removal of metabolic waste: carbon dioxide (lungs), urea (kidneys). Urea is made in the liver by deamination of excess amino acids. The kidney filters blood (glomerulus) and reabsorbs useful substances (glucose, water, some salts). Dialysis and transplants treat kidney failure.

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Excretion

Removal of metabolic waste: carbon dioxide (lungs), urea (kidneys). Urea is made in the liver by deamination of excess amino acids. The kidney filters blood (glomerulus) and reabsorbs useful substances (glucose, water, some salts). Dialysis and transplants treat kidney failure.

Homeostasis

Maintaining a constant internal environment by negative feedback.

  • Temperature control: sweating, vasodilation and vasoconstriction, shivering.
  • Blood glucose: insulin (lowers) and glucagon (raises), both from the pancreas; type 1 diabetes and its treatment.

The nervous system

Central and peripheral nervous systems; sensory, relay and motor neurones; reflex arcs; synapses (neurotransmitter diffuses across the gap). The eye: structure, accommodation and pupil reflex.

Hormones

Endocrine glands release hormones into the blood: adrenaline (fight or flight), insulin, glucagon, testosterone, oestrogen. Comparison of nervous and hormonal control.

Plant responses

Phototropism and gravitropism controlled by auxin.

Drugs

Medicinal drugs (antibiotics) and misused drugs (alcohol, heroin, tobacco); effects on the body and society.

Exam tip: For negative feedback questions, describe the detection, the response, and how the response reverses the change.

Check yourself

  1. Where is urea produced?
  2. Which hormone raises blood glucose?
  3. What happens to the pupil in bright light?
Show answers
  1. In the liver.
  2. Glucagon.
  3. It constricts (becomes smaller) – circular muscles of the iris contract.
Next topicReproduction, inheritance and evolution

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