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October 18, 2026

Inheritance and genetics

ZIMSEC O Level · Biology · Form 4

Key terms

  • Chromosome: thread of DNA in the nucleus; humans have 23 pairs.
  • Gene: a section of DNA that codes for a protein (characteristic).
  • Allele: a different form of a gene, e.g. tall (T) or short (t).
  • Dominant: shows whenever present. Recessive: shows only when two copies are present.
  • Homozygous: two identical alleles (TT or tt). Heterozygous: different alleles (Tt).
  • Genotype: the alleles present. Phenotype: the visible feature.

Monohybrid crosses

Worked example: Two heterozygous tall plants (Tt) are crossed. Find the expected offspring.

Gametes: T and t from each parent.

Offspring: TT, Tt, Tt, tt → 3 tall : 1 short.

Sex determination

Females are XX, males XY. Each child has a 50% chance of being a boy.

Variation and mutation

  • Continuous variation (height, mass) shows a range; discontinuous variation (blood group) falls into distinct groups.
  • A mutation is a change in a gene or chromosome. Radiation and some chemicals increase the rate.
  • Natural selection: individuals best suited to their environment survive and pass on their alleles. Artificial selection is used to breed high-yield maize or hardy cattle.
Exam tip: Always show gametes in circles and set out crosses with a Punnett square – method marks are awarded.

Check yourself

  1. Distinguish between genotype and phenotype.
  2. A homozygous dominant black bull (BB) is crossed with a red cow (bb). What colour are the calves?
  3. Give one example of continuous variation in humans.
Show answers
  1. Genotype is the alleles an organism has; phenotype is its observable characteristic.
  2. All black (Bb).
  3. Height or body mass.

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